SuperMethyl™ Max Early Access

Product Description

The SuperMethyl™ Max Bisulfite Conversion Kit delivers a revolutionary combination of ultra-mild chemistry and high conversion efficiency for low-input DNA methylation analysis. Engineered to preserve DNA integrity, this kit streamlines the bisulfite conversion workflow, achieving complete conversion with minimal degradation.

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With a total turnaround time of just 2–3 hours, SuperMethyl™ Max enables efficient bisulfite conversion and purification while maintaining exceptional DNA yield and fragment length—even from inputs as low as 100 pg. The kit consistently achieves >99.8% C-to-T conversion efficiency and produces uniform GC coverage across promoters and GC-rich regions.

Designed for sensitive and low-input samples, SuperMethyl™ Max ensures reliable, reproducible performance across diverse applications, from basic research to translational and clinical studies, making it the ideal choice for precision-focused researchers.

Ultra-Mild Conversion Chemistry

Delivers excellent DNA library yield and larger library insert sizes, preserving sample integrity.

Low-Input Friendly

Efficiently processes as little as 100 pg of DNA, ideal for limited or precious samples.

Exceptional Conversion Efficiency

Achieves 99.8% C-to-T conversion, ensuring unmatched accuracy in methylation analysis.

Uniform GC Coverage

Provides more even GC representation, enhancing coverage across promoters and GC-rich regions.

Simplified, Rapid Workflow

Up to 3× faster with 5× less hands-on time than enzyme-based methods.

Convenient Bead-Based Purification Format

Streamlined purification for improved yield and ease of use. Automation liquid handler friendly.

Data sheet

A comparison of SuperMethyl™ Max with the current methods.

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Press Release

New bisulfite chemistry delivers high-yield recovery and NGS compatibility for challenging epigenomic applications

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SuperMethyl^™ Max Bisulfite Conversion Kit