Applications

DNA methylation and epigenetics is revolutionizing many fields of basic, translational, and clinical research. Click below to learn about some key areas where 5mC methylation is important.

Cancer

DNA methylation patterns in circulating cell-free DNA (cfDNA) enable non-invasive cancer detection.

Development & Reproduction

DNA methylation undergoes dramatic reprogramming during early development and in germ cells.

Systems Epigenomics

Systems epigenomics integrates genome-wide methylation data with other molecular layers to understand gene regulation at scale.

Aging and Longevity

Biological age, measured through DNA methylation patterns, often diverges from chronological age.

Single Cell Epigenetics

Single-cell methylome techniques enable high-resolution mapping of epigenetic heterogeneity.