News & Articles
News
Chuan He on The Pulse Podcast: Epitranscriptomics & Biotech
The Pulse Podcast · Episode Summary Podcast Summary: Professor Chuan He on Innovation in Academia and Industry Hosted by Tanner Baldwin · Recorded at the University of Chicago In this episode of The Pulse, the Harvard Biotech Club's podcast, host Tanner...
Roche Highlights Robust Performance of Ellis Bio SuperMethyl™ Kits in New Tech Spotlight
Independent Roche evaluation shows SuperMethyl™ Max delivers the highest methylation calling accuracy in the study, producing fewer false calls than both a leading enzymatic methyl-seq (EM‑seq) method and a leading traditional bisulfite kit in low‑input cell-free DNA...
New Gentle Methyl Conversion Kit Delivers High-Accuracy Profiling from as Little as 100 pg of DNA
New commercial kit brings Nature Communications-validated methylation analysis chemistry to researchers working with low-input and cfDNA samples Cambridge, MA - Ellis Bio, a developer of next-generation epigenomics technologies, today announced the official...
New “Ultra-Mild” Sequencing Method Fixes Long-Standing Flaws in Cancer DNA Methylation Tests
Re-engineered bisulfite chemistry overcomes decades-old limitations in methylation sequencing Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was...
Ellis Bio and UChicago Announce Breakthrough Ultra-Mild Bisulfite Sequencing Technology
CAMBRIDGE, Mass. — Ellis Bio Inc., a genomics biotechnology company, announced the publication of a new bioRxiv preprint from the laboratory of its scientific founder, Professor Chuan He of The University of Chicago (UChicago)/Howard Hughes Medical Institute (HHMI),...
Exciting Innovations at ADLM 2025
Explore how Ellis Bio is revolutionizing DNA methylation analysis with their groundbreaking bisulfite conversion kits at ADLM 2025. Ellis Bio is attending ADLM 2025 Chicago, IL – The Association for Diagnostics & Laboratory Medicine (ADLM) in partnership with...
Articles
UMBS-seq vs. EM-seq: Ultra-Mild Bisulfite for Low Input
UMBS-seq (ultra-mild bisulfite sequencing) is a bisulfite conversion method developed by researchers at the University of Chicago that achieves highly efficient cytosine-to-uracil conversion — >99.8% in its downstream commercial kit form — while...
UBS-seq: The 7-Minute Bisulfite Conversion Method
UBS-seq (ultrafast bisulfite sequencing) is a bisulfite conversion method developed by researchers at the University of Chicago that converts unmethylated cytosines to uracil in as little as 10 minutes or less, allowing the total methyl conversion protocol to be...
Ellis Bio unveils SuperMethyl™ Max kit for low-input DNA methylation workflows
New bisulfite chemistry delivers high-yield recovery and NGS compatibility for challenging epigenomic applications Chicago, IL – Ellis Bio Inc, a biotechnology company accelerating innovation in epigenomics, today announced the launch of its SuperMethyl™ Max Kit, the...
The Top 5 Tips for Conducting DNA Methylation Experiments
DNA methylation is a crucial epigenetic modification that plays a significant role in gene regulation, development, and disease progression. In this blog post, we discuss 5-methylcytosine (5mC), which is the most commonly studies epigenetic mark. Researchers studying...