Re-engineered bisulfite chemistry overcomes decades-old limitations in methylation sequencing Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was...
The SuperMethyl™ Max Bisulfite Conversion Kit delivers a revolutionary combination of ultra-mild chemistry and high conversion efficiency for low-input DNA methylation analysis. Engineered to preserve DNA integrity, this kit streamlines the bisulfite conversion workflow, achieving complete conversion with minimal degradation.
$194.99
With a total turnaround time of just 2–3 hours, SuperMethyl™ Max enables efficient bisulfite conversion and purification while maintaining exceptional DNA yield and fragment length—even from inputs as low as 100 pg. The kit consistently achieves >99.8% C-to-T conversion efficiency and produces uniform GC coverage across promoters and GC-rich regions.
Designed for sensitive and low-input samples, SuperMethyl™ Max ensures reliable, reproducible performance across diverse applications, from basic research to translational and clinical studies, making it the ideal choice for precision-focused researchers.
Delivers excellent DNA library yield and larger library insert sizes, preserving sample integrity.
Efficiently processes as little as 100 pg of DNA, ideal for limited or precious samples.
Achieves 99.8% C-to-T conversion, ensuring unmatched accuracy in methylation analysis.
Provides more even GC representation, enhancing coverage across promoters and GC-rich regions.
Up to 3× faster with 5× less hands-on time than enzyme-based methods.
Streamlined purification for improved yield and ease of use. Automation liquid handler friendly.
SuperMethyl Max incorporates Ultra-Mild Bisulfite technology (Nature Communications Publication In Press) for optimal reaction conditions.
The gentle conversion condition and shortened conversion time minimizes DNA degradation, while the greater conversion efficiency improves accuracy.
A comparison of SuperMethyl™ Max with the current methods.
New bisulfite chemistry delivers high-yield recovery and NGS compatibility for challenging epigenomic applications