SuperMethyl™ Max Bisulfite Conversion Kit
Enzyme-like bisulfite conversion that preserves DNA integrity, ideal for low-input applications with industry-leading accuracy.
The SuperMethyl™ Max Bisulfite Conversion Kit delivers a revolutionary combination of ultra-mild chemistry and high conversion efficiency for low-input DNA methylation analysis. Engineered to preserve DNA integrity, this kit streamlines the bisulfite conversion workflow, achieving complete conversion with minimal degradation.
$194.99
More Information
With a total turnaround time of just 2–3 hours, SuperMethyl™ Max enables efficient bisulfite conversion and purification while maintaining exceptional DNA yield and fragment length—even from inputs as low as 100 pg. The kit consistently achieves >99.8% C-to-T conversion efficiency and produces uniform GC coverage across promoters and GC-rich regions.
Designed for sensitive and low-input samples, SuperMethyl™ Max ensures reliable, reproducible performance across diverse applications, from basic research to translational and clinical studies, making it the ideal choice for precision-focused researchers.
Benefits
Ultra-Mild Conversion Chemistry
Delivers excellent DNA library yield and larger library insert sizes, preserving sample integrity.
Low-Input Friendly
Efficiently processes as little as 100 pg of DNA, ideal for limited or precious samples.
Exceptional Conversion Efficiency
Achieves 99.8% C-to-T conversion, ensuring unmatched accuracy in methylation analysis.
Uniform GC Coverage
Provides more even GC representation, enhancing coverage across promoters and GC-rich regions.
Simplified, Rapid Workflow
Up to 3× faster with 5× less hands-on time than enzyme-based methods.
Convenient Bead-Based Purification Format
Streamlined purification for improved yield and ease of use. Automation liquid handler friendly.
HOW IT WORKS
SuperMethyl Max incorporates Ultra-Mild Bisulfite technology (Nature Communications Publication In Press) for optimal reaction conditions.
The gentle conversion condition and shortened conversion time minimizes DNA degradation, while the greater conversion efficiency improves accuracy.
Additional Resources
Data sheet
A comparison of SuperMethyl™ Max with the current methods.
Press Release
New bisulfite chemistry delivers high-yield recovery and NGS compatibility for challenging epigenomic applications
Protocol
Detailed instructions for using our SuperMethyl™ Max Bisulfite Conversion Kit.