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SuperMethyl™ Fast Bisulfite Conversion Kit

The fastest C-to-U conversion method on the market-just 35 minutes end-to-end
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Product Description

SuperMethyl™-Fast Bisulfite Conversion Kit delivers the fastest and most efficient bisulfite conversion solution available for DNA methylation analysis. Simply add the newly engineered, ready-to-use reagent Bisulfite Conversion Reagent to your DNA sample and incubate for just 7 minutes.

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MORE INFORMATION

Beyond speed, SuperMethyl™-Fast ensures exceptional precision, achieving >99.5% conversion efficiency and superior methylation protection. With a total protocol time of only 35 minutes, this kit provides rapid, reliable, and highly reproducible results, making it the ideal choice for researchers who demand both accuracy and quick turnaround.

Bisulfite Conversion Gets a Major Speed Upgrade

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Benefits

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Fastest Conversion Available

10X faster than leading industry kits
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Exceptional Performance

Excellent methylation protection; Compatible with a wide range of DNA inputs.
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Versatile Applications

Optimized for PCR, microarrays, endonuclease digestion, and next-generation sequencing (NGS).
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Cost-Effective

At just $179.99, competitively priced with a price-match guarantee.

Specifications

INPUT

10 ng - 2 μg purified DNA
(gDNA, cfDNA, FFPE)

 

CONVERSION EFFICIENCY

>99.5%

 

DNA RECOVERY

>80%

 

ELUTION VOLUME

Beads: 30 μL
Column: 10-30 μL

 

COMPATABILITY

KAPA Library kits (Roche), xGen Methyl-Seq kit (IDT)

 

Input

10 ng - 2 μg purified DNA
(gDNA, cfDNA, FFPE)

Conversion Efficiency

>99.5%

DNA Recovery

>80%

Elution Volume

Beads: 30 μL
Column: 10-30 μL

Compatibility

KAPA Library kits (Roche), xGen Methyl-Seq kit (IDT)

HOW IT WORKS

  1. SuperMethyl Fast kits incorporate an optimized Ultrafast Bisulfite technology for efficient reaction conditions.
  2. Optimal conditions maximize C-to-U conversion while minimizing degradation.
  3. Proprietary ready-to-use reagents eliminate the need for mixing.
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FEATURED IN NATURE BIOTECHNOLOGY

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mESC gDNA  converted with SuperMethylTM Fast and other suppliers’ bisulfite conversion kits. C-to-T conversion ratios were determined post-sequencing using unmethylated λ-DNA spike-in control. 
 
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mESC gDNA with 1% unmethylated lambda DNA spike-in were converted with SuperMethylTM Fast and other suppliers’ bisulfite conversion kits. False positive rates were calculated post-NGS as the percentage of CpG and non-CpG cytosines showing >1% unconverted C. 

Additional Resources

SuperMethyl™ Fast Data Sheet

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50 Reactions Beads Protocol

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50 Reactions Columns Protocol

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